Dear Foregen supporters,

Thanks to your support, we are preparing for the next phase of our research: human clinical trials! Here are the updates from last month:

Animal Trials Final Report

The results of the sheep study have been finalized and compiled into a comprehensive final report. This will be submitted for publication shortly, and we are confident it will appear in a reputable academic journal early next year. Most importantly, Foregen does not need to wait for these reports to be published to continue progressing toward human clinical trials. This has been made possible thanks to your exceptional support this year.

HistologiX Histology Study

All 18 tissue samples have been received and processed by HistologiX. The next step involves conducting the staining. The unique markers chosen to characterize the distinct structures in the prepuce samples have already been selected by HistologiX and approved by CSO William Musa. We anticipate that the histology study will be completed by the end of the year, with the results being published in early 2025.

Dr. José Vega

An additional histology study has been commissioned from Dr. José Vega, focusing on the density of specialized nerve structures, such as Meissner’s Corpuscles, in the human foreskin. The study is expected to be completed by mid-December and will be submitted for publication in an academic journal shortly thereafter. The findings will inform our efforts to achieve reinnervation for circumcised men.

Preparing for Human Trials

We are continuing to identify and communicate with potential research partners for the human trials planned for 2025. We are excited to share more details about our plans as soon as possible.

New Donation Methods Added

Exciting news for donors holding crypto, stocks, mutual funds, or donor-advised funds (DAFs)! We’ve recently added new functionality to our website, enabling Foregen supporters to contribute through these innovative donation methods. Visit our donation page to explore these options! No matter how you choose to donate, every gift you provide plays an instrumental role in advancing our research toward our ultimate goal.

Fundraising

Thanks to our incredibly generous and supportive community, Foregen raised a total of $17,139 in November! These funds are vital for preparing for our future human clinical trials, and we are deeply grateful for your support.

Your contributions can make a significant difference. Join us in developing the world’s first regenerative medicine solution for circumcised men!

Sincerely,

Ryan Jones

Chief Operations Officer